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The Showa Denko Tryptophan disaster
The tryptophan disaster in the end of the 1980’s and beginning of 1990’s killed 37 and permanently disabled 1,500 people in the United States in a disease called eosonophil myalgia syndrome (EMS).
It was caused by one or more extremely poisonous substances present in a tryptophan food supplement, which was produced by genetically engineered bacteria at the Japanese firm Showa Denko.
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